2020

June 01, 2020
Pharmacokinetics and pharmacodynamics of TTI-101, a STAT3 inhibitor that blocks muscle proteolysis in rats with chronic kidney disease

April 09, 2020
Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 to Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution

February 26, 2020
Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40

2019

April 26, 2019
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ERpositive breast cancer

2018

August 05, 2018
Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment

2017

August 15, 2017
Role of STAT3 in Skin Fibrosis and Transforming Growth Factor Beta Signalling

May 22, 2017
Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice

2016

August 01, 2016
STAT-3 contributes to Pulmonary Fibrosis through Epithelial Injury and Fibroblast-Myofibroblast

August 01, 2016
STAT3 Inhibitors in Cancer: A Comprehensive Update

May 21, 2016
STAT3 Inhibition Prevents Lung Inflammation, Remodeling, and Accumulation of Th2 and Th17 Cells in a Murine Asthma Model

March 25, 2016
Small-molecule Inhibition of STAT3 in Radioresistant Head and Neck Squamous Cell Carcinoma

2015

November 06, 2015
Diminution of Signal Transducer and Activator of Transcription 3 Signaling inhibits Vascular Permeability and Anaphylaxis

September 14, 2015
Small-molecule targeting of Signal Transducer and Activator of Transcription (STAT) 3 to treat Non-Small Cell Lung Cancer

April 24, 2015
Inhibition of STAT3 Activation Suppresses Caspase-3 and the Ubiquitin-Proteasome System, Leading to Preservation of Muscle Mass in Cancer Cachexia

2013

September 03, 2013
STAT3 Activation Links a C/EBPd to Myostatin Pathway to Stimulate Loss of Muscle Mass

2011

May 26, 2011
STAT3 Signaling in Acute Myeloid Leukemia: Ligand-dependent and -independent Activation and Induction of Apoptosis by a novel Small-molecule STAT3 Inhibitor

2009

March 10, 2009
Chemical Probes that competitively and selectively Inhibit STAT3 Activation